看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。% y( o' [, w. ]2 H8 C5 W( w
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* N* \: w: j& p: MCurrently available feasibility data for possible combination strategies. ! k! g1 c2 ]. W- P( k
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8 k- C5 B' l6 Y. @ i0 o9 |Combination Feasibility according to preliminary data
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; A5 ^: W- R3 I- p; pBevacizumab + sorafenib Yes, reduced dose / P% a8 t6 ]% B4 d
Bevacizumab + sunitinib† No
3 \; r w8 h0 n! H8 ^: SBevacizumab + temsirolimus Yes 1 T4 a8 b0 h7 U& u+ q
Bevacizumab + everolimus Yes
5 y$ A5 w7 a1 eSorafenib + sunitinib ? : i9 K9 P% I! l% P
Sorafenib + temsirolimus Yes, reduced dose
( _7 a* h/ ]7 ?3 M' g6 o, S" t' ~Sorafenib + everolimus Yes, reduced dose
/ f; k. l+ G3 d- K' ^* zSunitinib + temsirolimus† No
! t( l4 A! |: V5 b, Y5 YSunitinib + everolimus ?
8 ]) x8 L3 c5 U: k$ [6 N( ~$ c' I$ aTemsirolimus + everolimus ?
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- Y' I( x$ D, S3 T g†Led to US FDA warning.1 t& B; c2 ^+ Z7 \
?: As yet unattempted combination.
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